BIOLOGICAL INDICATORS OF CHEMORESISTANCE: AN EX VIVO ANALYSIS OF γH2AX AND P53 EXPRESSION IN FELINE INJECTION-SITE SARCOMAS

Biological indicators of chemoresistance: an ex vivo analysis of γH2AX and p53 expression in feline injection-site sarcomas

Abstract Background The response of soft tissue sarcomas to cytotoxic chemotherapy is inconsistent.Biomarkers of chemoresistance or chemosensitivity are needed in order to identify appropriate patients for treatment.Given that many chemotherapeutics kill cells through direct DNA interactions, we hypothesized that upregulation of DNA damage response

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Long live the king: chromosome-level assembly of the lion (Panthera leo) using linked-read, Hi-C, and long-read data

Abstract Background The lion (Panthera leo) is one of the most popular and iconic feline species on the planet, yet in spite of its popularity, the last century has seen massive declines for lion populations worldwide.Genomic resources for endangered species represent an important way forward for the field of conservation, enabling high-resolution

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Signatures of criticality in turning avalanches of schooling fish

Moving animal groups transmit information through propagating waves or behavioral cascades, exhibiting characteristics akin to systems near LONG SLEEVE RASHGUARD a critical point from statistical physics.Using data from freely swimming schooling fish in an experimental tank, we investigate spontaneous behavioral cascades involving turning avalanche

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GPS Spoofing Detection using CAF Images and Neural Networks Based on the Proposed Peak Mapping Dimensionality Reduction Algorithm and TCNN Model

Global Positioning System (GPS)-based positioning has become an indispensable part of our daily lives.A GPS receiver calculates its distance from a 5 Piece Dining Set satellite by measuring the signal reception delay.Then, after determining its position relative to at least four satellites, the receiver obtains its precise location in three dimensi

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